Counterclockwise Profhilo
目次
Profhilo high and low molecular weight hyaluronic acid subcutaneous implant - Ministry of Health and Welfare Medical Device Registration No. 037968
What is Profhilo counterclockwise?
Profhilo's official Chinese name is "璞菲洛高低分子玻尿酸皮下植入劑" (Ministry of Health Medical Device Import Number 037968). This injectable product focuses on the conditioning and activation of skin structure, developed by the Swiss pharmaceutical company IBSA. It is currently sold in over 90 countries worldwide and has accumulated 65 patents, providing another option for those seeking skin rejuvenation.

Unlike common hyaluronic acid fillers or collagen stimulators, Profhilo is classified as a "skin remodeling agent." It utilizes the patented NAHYCO® technology, combining high molecular weight and low molecular weight hyaluronic acid (HMW/LMW HA) to form a stable HCCs synergistic complex containing 64 mg per 2 mL. The product only needs to be injected at a few designated points to evenly diffuse within the dermis, promoting the generation of collagen I, III, IV, and VII, as well as activating elastin, thereby enhancing skin firmness and improving sagging.
The effects and applicable areas of Profhilo®.
Counterclockwise injection focuses on deep hydration and collagen activation, and can be used in multiple areas that easily show signs of aging, including the face, neck, back of the hands, upper chest, arms, knees, and abdomen. Its main benefits are summarized as follows:
| Effect | 說明 |
|---|---|
| Deep hydration and moisturizing | High concentration hyaluronic acid molecules penetrate the dermis layer, maintaining moisture for a long time, making the skin look more hydrated. |
| smooth texture | Improves nasolabial folds, crow's feet, marionette lines, neck lines, and other wrinkles and localized depressions. |
| contour support and tightening | By activating fibroblasts, it promotes the production of collagen and elastin, helping to enhance elasticity and firmness. |
| skin quality conditioning | Improve skin tone evenness, reduce roughness and visible pores, and help repair mild acne scars and depressed scars. |
Profhilo injection interval and maintenance recommendations
Initial treatment
A total of 3 injections.
Recommended interval: The 1st and 2nd sessions should be about 4 weeks apart; the 3rd session can be scheduled 4-6 months after the 2nd session.
Purpose: To initiate the continuous proliferation of collagen and elastin, laying the foundation for subsequent maintenance.

Strengthening Phase
After completing 3 sessions, if you want to further enhance the tightening effect, you can add 1 more session after 4 to 6 months.
The doctor will adjust the schedule according to individual skin conditions (dryness, degree of laxity, etc.).
Maintenance recommendation: Repeat one treatment cycle every 6–12 months to help prolong the effects.

Groups not suitable for Profhilo®
- Injection area inflammation, infection, or eczema
- Pregnancy or breastfeeding period
- Allergic to HA or crosslinking agents
- Coagulation function abnormalities or long-term use of anticoagulant drugs
- Scar constitution or tendency to keloids

Post-operative recovery and precautions
- Usually, there is no recovery period required, and a small number of people may experience slight swelling or red spots, which gradually disappear within 1-2 days.
- Avoid high temperature environments (such as saunas), intense exercise, or alcohol for 24 hours.
- Focusing on hydration and sun protection helps hyaluronic acid retain moisture and supports collagen production.
Medical certificate


